Digital polymerase chain reaction (PCR) is a quantitative method that provides a reproducible and sensitive way of measuring the DNA and RNA count present in the sample.
It is a simple and reproducible way and doesnt depend on the calibration curve for sample target quantification. Digital PCR is a robust method in molecular testing and has a wide range of applications it includes copy number variations, improved rare allele detection, and pathogen detection, viral load detection and improved sensitivity for detecting a target in limited clinical samples and enhanced multiplexing capabilities.
Digital PCR technology is being consistently expanded upon and companies are focusing on developing a solution with improved accuracy in detection, sensitivity and result time.
The rise in the incidence of infectious disease and genetic disorders, increase in the adoption of digital PCR technology by clinal laboratories and diagnostic centers for pathological diagnosis and continuous technological growth to meet the market demand are driving the global digital PCR market during the forecast period.
Owing to its increase in accuracy, sensitivity, robustness, and reproducibility by digital PCR, it has its potential to play a significant role in diagnosis, prognosis, and therapeutics in precision medicine.
According to Health Knowledge a learning resource for healthcare professionals in 2017, while birth, individually they are rare but collectively genetic disorders are relatively familiar with a combined prevalence of 1-2% in U.K. around 4,000 inherited diseases are known to be associated with mutations in single genes, with responsible patterns of inheritance.
Major factors hindering the global digital PCR market are a high cost associated with digital PCR devices and limitations of digital PCR technology.
Global digital PCR market is segmented by technology type, product type, application type, and end users. By technology type includes droplet digital PCR technology, beaming digital PCR technology, product type includes systems, kits& reagents, software, and services. Application type includes clinical diagnostic, research, forensics, and others, and end users include research organizations, clinical diagnostic laboratories, educational institutions, and others.
Software and services segment dominates the global digital PCR market during the forecast period due to its importance associated with the digital PCR systems as they improve efficiency by solving the repetitive task and focuses on delivering useful output, increase in adoption of this equipment by the potential end users and research organizations.
The global digital PCR market is segmented into North America, Europe, Asia Pacific, South America, and Middle East & Africa.
North America dominates the global digital PCR market due to the presence of critical molecular diagnostic manufacturers across the region and increases patient preference towards personalized medicine, and it is expected to remain high during the forecast period. The rise in the presence of a chronic disease population across the region and improved healthcare infrastructure is additionally contributing to the growth during the forecast period.
According to National Cancer Institute in 2018 estimated that approximately 1,735,350 new cancer will be diagnosed, as these digital PCR systems are used to detect and quantify cancer-causing genes in the patients is expected to drive the market in North America during the forecast period.
Few product launches and Research &development initiatives by critical players for the development of advanced technology based PCR technology systems for improving its efficiency, sensitivity and through output are driving the global digital PCR market during the forecast period.
On February 20th, 2019, Stella Technologies launched High-Throughput digital PCR chip and initiated R&D of the six-color system.
On February 15th, 2019, Bio-Rad launched new digital PCR system and kit for monitoring treatment response in chronic myeloid leukemia patients.
In January 2019, QIAGEN N.V announced the development of a range of next-generation systems for digital PCR(an integrated solution) by 2020.
In March 2018, Stella technologies Paris based European biotechnology launched next generation crystal digital PCR technology for absolute quantification of nucleic acids.
In January 2017, JN Medsys launched next-generation digital PCR system with greater sensitivity and high detection throughput.
Major market players in the digital PCR market are Bio-Rad Laboratories, Thermo Fisher Scientific, Fluidigm Corporation, JN Medsys, Sigma-Aldrich, Qiagen N.V, Stella Technologies, Formulatrix, and others.
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