Molecular biology and cytogenetics are the two primary fields which are studied under molecular cytogenetics. The study of chromosomes is termed as Cytogenetics. Molecular cytogenetics further delves into the analysis of genetic variations and/or alterations through in-situ hybridization techniques.
Growing cases of congenital & genetic disorders coupled with the subsequent rise in the early disease diagnostics are the primary factors driving the growth of this market in the aforementioned forecast period. Secondly, the advent of enhanced, entire genome screening techniques (which comprise chromosome microarray analysis and multiplex FISH) because of the technological advancements in the cytogenetic techniques namely, Comparative Genomic Hybridization (CGH) and the Fluorescence in-situ hybridization (FISH). These highly advanced, high-throughput tools help in identifying therapeutic targets, for example, oncogenes that are implicated in tumorigenesis, besides determining the presence of chromosomal aberrations for the diagnosis of genetic diseases thereby driving the growth of this market. Emergence of rapid testing platforms for the characterization of chromosomal aberrations with very high precision conjoined with the development of diagnostic tools that are highly sensitive will propel the growth of this market. Genetic disorders claim over 3000 infant lives per year as per the data published by the Centres for Disease Control and Prevention. Molecular diagnostic techniques such as FISH and CGH are expected to witness high penetration because of such high mortality rates. Next generation sequencing technology which enables comprehensive and cost-effective analyses is another factor contributing to the growth of this market.
The Latin America Molecular Cytogenetics market can be categorized into four categories: by product, by technique, by application and by end user. On the basis of product, Latin America Molecular Cytogenetics market is classified into Kits & Reagents, Instruments, Consumables, and Software & Services. Kits and Reagents is further segmented into Testing Kits, Probes, Fluorescent Affinity Reagents and Other Kits & Reagents. If we go by technique, Latin America Molecular Cytogenetics market is segmented into Comparative Genomic Hybridization, Fluorescence in Situ Hybridization, In Situ Hybridization, and Other Techniques. The CGH technology category commands the largest market share of approximately 53% and is estimated to retain its leading position over the aforementioned forecast period. Rising levels of awareness regarding the CGH techniques in molecular biology is likely to raise patient acceptance and widen the application horizon in molecular diagnostics. In addition, effective cancer diagnosis because of the characterization of novel diagnostic biomarkers coupled with the development of high-resolution, genetic testing platforms which diagnose constitutional and acquired diseases are vital to the growth of this market segment.
Rising number of applications regarding the detection of complex chromosomal arrangements using multicolour FISH techniques and SNP-array analysis is another one of the contributing factors for the growth of this segment. Further, Comparative Genomic Hybridization is segmented into Array-Based Comparative Genomic Hybridization and Standard Comparative Genomic Hybridization. In addition, on the basis of application the market can be categorized into Genetic Disorders, Cancer, Personalised Medicine, and Other Applications. Cancer was the biggest application category in terms of revenue as per the data of 2014 accounting for over 42% of the overall molecular cytogenetics market. Rising cases of various types of cancer coupled with the rising demand for high-throughput diagnostic tools is expected to boost the usage rate of the molecular cytogenetic technologies over the aforementioned forecast period. Personalized medicine segment is poised to widen the therapeutic horizons in delivering enhanced, molecularly guided therapies, and precise monitoring of disease progression thereby leading to the growth of this market segment. Last but not the least, on the basis of end user the market is segmented into Clinical & Research Laboratories, Academic Research Institutes, Pharmaceutical & Biotechnology Companies and Other End Users.
By geography, the Latin America Molecular Cytogenetics market has been categorized into Brazil, Argentina, Chile and other countries of South America. It is second to last in terms of market share. Brazil is the leading country in the region.
Affymetrix, Inc., Agilent Technologies, Inc., Illumina, Inc., Abbott Laboratories, Bio-Rad Laboratories, Inc., Applied Spectral Imaging, Inc., and Thermo Fisher Scientific (Life Technologies), Inc. are some major players operating in the molecular cytogenetics market.
Market Segmentation : 1) Product 2) Technique 3) Application 4) End User
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