(PharmaNewsWire.Com, November 16, 2017 ) The global cell culture media market is growing exponentially and is expected to grow at the same pace during the forecast period at a CAGR of ~ 9.1%
A cell culture medium is a growth medium designed to support the growth of cells. A cell culture medium is composed of appropriate composition of amino acids, vitamins, inorganic salts, glucose, serum, etc. It may contain additional supplementary factors such as growth factors, hormones, etc., depending on the need of different types of cells.
Cell Culture Media Market are classified into natural media and synthetic media. Natural media consist of naturally occurring biological fluids, while synthetic media have additional components such as serum proteins, carbohydrates, cofactors, vitamins, salts etc. The Natural media has poor reproducibility due to lack of knowledge about exact composition in this media.
Artificial media are further sub-segmented into various types such as serum containing media, serum-free media, chemically defined media, and protein-free media. To overcome the drawbacks of serum in the media, a number of serum-free media have been developed. Chemically defined media contains inorganic and organic ingredients. Protein-free media only contains non-protein constituents to promote superior cell growth and protein expression.
The market for cell culture media is growing at an impressive rate due to various factors such as growing number of biotech firms, growing demand for biotechnology products, high returns on investments, technological advancements, etc. However, contamination of cell culture media, presence of heavy trace elements, high cost of final products, lack of scientific understanding of natural media, issues of reproducibility, quality and specificity, especially, of natural media, scarcity of serum and animal components, ethical issues regarding use of animal components, etc may hamper the growth of the market.
Key Players for Cell culture media Market:
Merck KGaA, Corning Incorporated, GE Healthcare, Thermo Fisher, Lonza, BD, HiMedia Laboratories, and others.
Primary cultures are derived directly from excised, normal animal tissue and cultures either as an explant culture or following dissociation into a single cell suspension by enzyme digestion. Such cultures are initially heterogeneous but later become dominated by fi broblasts. The preparation of primary cultures is labour intensive and they can be maintained in vitro only for a limited period of time. During their relatively limited lifespan primary cells usually retain many of the differentiated characteristics of the cell in vivo.
5.2 Continuous Cultures
Continuous cultures are comprised of a single cell type that can be serially propagated in culture either for a limited number of cell divisions (approximately thirty) or otherwise indefi nitely. Cell lines of a fi nite life are usually diploid and maintain some degree of differentiation. The fact that such cell lines senesce after approximately thirty cycles of division means it is essential to establish a system of Master and Working banks in order to maintain such lines for long periods.
Continuous cell lines that can be propagated indefi nitely generally have this ability because they have been transformed into tumour cells. Tumour cell lines are often derived from actual clinical tumours, but transformation may also be induced using viral oncogenes or by chemical treatments. Transformed cell lines present the advantage of almost limitless availability, but the disadvantage of having retained very little of the original in vivo characteristics.
5.3 Culture Morphology
In terms of growth mode cell cultures take one of two forms, growing either in suspension (as single cells or small free fl oating clumps) or as a monolayer that is attached to the tissue culture fl ask. The form taken by a cell line refl ects the tissue from which it was derived e.g. cell lines derived from blood (leukaemia, lymphoma) tend to grow in suspension whereas cells derived from solid tissue (lungs, kidney) tend to grow as monolayers. Attached cell lines can be classifi ed as endothelial such as BAE-1, epithelial such as HeLa, neuronal such as SH-SY5Y, or fi broblasts such as MRC-5 and their morphology refl ects the area within the tissue of origin.
The global cell culture media market is expected to reach USD 1,290.1 million by 2023
Lysogeny broth segment is expected to command the largest market share of 22.5% and is expected to reach USD 298.6 million by the end of 2023. This market is expected to grow at a CAGR of 9.5% during the forecast period 2017-2023
Drug discovery and drug development segment led the largest market share of around 23.8% in 2016. This market is expected to reach USD 315.3 million in 2023 and is expected to grow at a CAGR of 9.5% during the forecast period 2017-2023
Biotechnology & pharmaceutical companies segment is expected to command the largest market share of around 29.3% in 2016. This market is expected to reach USD 386.5 million in 2023 from at a CAGR of 9.4% during the forecast period 2017-2023
North Americas region held the largest market share of 36.1% in 2016. This market is expected to reach USD 478.7 million by 2023 at a CAGR of 9.5% during the forecast period 2017-2023. However, the Asia Pacific market is expected to grow at the fastest CAGR of 9.6% during the forecast period 2017-2023.
Segments:
Cell culture media market is segmented on the basis of type, application, and end users.
On the basis of type, the market is segmented into lysogeny broth, chemically defined media, protein free media, serum free media, classical media, custom media, and others.
On the basis of applications, the global cell culture market is segmented into drug discovery and drug development, toxicity testing, cancer research, genetic engineering, tissue engineering & biochemistry, stem cell research, and others.
On the basis of end users, the global cell culture market is segmented into biotechnology & pharmaceutical companies, research laboratories, academic institutes, pathology labs, and others.
On the basis of region, the global cell culture market is segmented into North Americas, Europe, Asia Pacific, and the Middle East & Africa.
Regional Analysis of Cell Culture Media Market:
Considering the global scenario of the market, North Americas region accounted for the largest market share of 36.1% in 2016. This market is expected to reach USD 478.7 million by 2023 at a CAGR of 9.5 % during the forecast period 2017-2023. Europe is expected to be the second largest global cell culture market in terms of regions and is expected to reach USD 374.3 million at a CAGR of 9.3 % during the forecast period 2017-2023. However, the Asia Pacific market is expected to grow at the fastest CAGR of 9.6 % during the forecast period 2017-2023.
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